+ Perioperative Medicine

• Dr. Held's Perioperative Medicine Updates PPT (with questions)
• ACC Decision Pathway for Periprocedural Management of Anticoagulation in Patients With Nonvalvular Atrial Fibrillation - 2017
• Preoperative Chest X-rays: A Teachable Moment
• Management of Antithrombotic Therapy in Patients Undergoing Invasive Procedures
• ACS NSQIP Surgical Risk Calculator
• MDCALC - Revised Cardiac Risk Index for Pre-Operative Risk
• Preoperative Medication Management - Johns Hopkins hospitalist CME module.
• JCC Bridging Anticoagulation

+ Medicine Consultation

• Principles of Effective Consultation: An Update for the 21st-Century Consultant

+ ACLS

• ACLS Refresher
  • N.b. We still have access to our ACLS modules online, find the login information in your emails by searching "ACLS", it may be in your personal email - www.onlineaha.org

• Ischemia

• Chest Pain Guidelines
• AHA/ACC Guidelines for Lipids
• COURAGE Trial - PCI vs. medical tx for stable CAD
• PROVE-IT - high intensity statin
• CURE trial - ASA+clopidogrel in NSTEMI
• CABG review - NEJM 2016
• PRODIGY Trial - DAPT 12 vs 30 mos
• PCSK9 inhibitor (alirocumab) for hypercholesterolemia

• Arrhythmia

• ACC/AHA Guidelines on Ventricular Arrhythmia
• Atrial Fibrillation Guidelines
• AFFIM Trial - rate vs rhythm AFib
• RACE-II - intensive vs liberate rate control AFib
• ROCKET-AF - Rivaroxaban in AF
• RE-LY - Dabigatran in AF
• ARISTOTLE - Apixiban in AF
• SPAF Trial - ASA or warfarin in AF
• SVT Reviewed Paper NEJM
• Syncope NEJM
• How to Identify Cardiac Device

• Heart Failure

• AHA/ACC Guidelines for Management of Heart Failure
• CONSENSUS - ACEi in HFrEF
• COMET - carvedilol in HFrEF
• RALES - spironolactone in HFrEF (III-IV)
• EMPHASIS-HF - eplerenone in HFrEF (II-IV)
• MADIT-CRT - CRT in HFrEF
• CHFpEF Review Paper
• Cardiorenal Syndrome - circulation reviews
• PARADIGM-HF - ARNI (sucubitril)

• Valvular Disease

• Valvular Heart Disease Guidelines
• AS Review article
• PARTNER Trial - TAVR for AS

+ Gastroenterology

ACG Guidelines

• Benign Anorectal Disorders
• Acute Pancreatitis
• C. difficile
• GERD
• Celiac Disease
• Idiosyncratic Drug-Induced Liver Injury
• Ulcer Bleeding
• Management and Prevention of Variceal Bleeding

IBD

• Crohn's Disease Review
• Systematic Review: IBD and C. difficile
• Ulcerative Colitis in Adults

Diarrhea

• Acute Infectious Diarrhea NEJM
• Celiac Disease: Ten Things every GI Should Know
• Microscopic colitis - Gastroenterology

UGIB

• Management in PUD UGIB
• Gastrointestinal angiodysplasia Review Article
• Gastric Antral Vascular Ectasia (GAVE) Syndrome

LGIB

• Diagnosis and Management of LGIB

Pancreatitis

• Guidelines for Interventions on Necrotizing Pancreatitis

+ Hepatology

• Acute Liver Failure NEJM
• Colonoscopy in Liver Disease
• Alcohol Use in Adults NEJM
• AASLD Guidelines:
  • Alcoholic Liver Disease
  • Hepatic Encephalopathy
  • Chronic Hepatitis B
  • Liver Transplant Evaluation
  • Nonalcoholic Steatohepatitis
  • Bleeding in Cirrhosis
  • Primary Billiary Cirrhosis
  • Primary Sclerosing Cholangitis
  • TIPS in Liver Disease
  • Wilson's Disease

+ Landmark Articles

• Coming soon

+ Guidelines

• Skin and Soft Tissue Infections
• Endocarditis - Management
• Endocarditis - Prevention
• Bacterial Meningitis
• Community Acquired Pneumonia
• Hospital Acquired & Ventilator Associated Pneumonia
• Find all the IDSA guidelines here

+ Acute Renal Failure

• JAMA: ARF ReviewA
• NEJM: ARF and Sepsis
• Prerenal/Ischemic AKI
• ARF - Review
• AAFP: Urinalysis Review
• Urine Micro accuracy for AKI

+ Acute Tubular Necrosis

• Annals: Diagnosis and Treatment of ATN
• NEJM: Normotensive Ischemic ARF

+ Miscellaneous

• JACC: Cardiorenal Syndrome Review
• JASN: Intra-Abdominal HTN/ACS Brief Review
• NEJM: TLS Review

+ Chronic Kidney Disease

• NEJM: Uremia
• NEJM: Stage IV Chronic Kidney Disease
• ACP: In the Clinic Series - CKD Review
• Mayo: Top 10 Things PCPs Should Know About CKD
• NEJM: ACEi in Advanced Non-DM CKD

+ Diabetic Kidney Disease

• Cochrane Rev: ACEi/ARBs progression of DM Nephropathy
• NEJM: ARB in DM pts with proteinuria
• NEJM: RENAAL Trial Losartan in DM
• Cochrane Review: ACE/ARBs decrease ESRD

+ Dialysis

• NEJM: Hemodialysis - Medical Progress Review
• NEJM: CRRT for AKI - Clinical Therapeutics Review
• NEJM: Ultrafiltration in CHF with Cardiorenal Syndrome
• CJASN: To dialyze or not - Case discussion of AKI in the ICU

+ Transplant

• NEJM: Immunosuppressive Drugs for Kidney Transplantation

+ Electrolytes

Sodium

• NEJM: SIADH Review
• NEJM: Hyponatremia Review
• AJKD: Review of Vaptan Physiology and Use in Hyponatremia
• AJKD: Beer Potomania
• NEJM: Hypernatremia

Potassium/Magnesium

• NEJM: Current Concepts-Hypokalemia Review
• JASN: Hypokalemia causes hypomagnesemia-mechanism

Acid-Base

• Acid Base Review by Adrogue-1/2 NEJM
• Acid base Review by Adrogue-2/2 NEJM

+ Hypertension

• JAMA: JNC-8 Guidelines
• NEJM: Na and K in pathogenesis of HTN

Secondary HTN and Specific Populations

• AHA: Renovascular HTN/Ischemic Nephropathy
• AAFP: Diagnosis of Secondary Hypertension: An Age-Based Approach
• Clinical Endo: Primary Hyperaldo-general review.
• Nature: Primary Hyperaldo-Diagnosis and Treatment Strategies

+ Glomerulonephritis and Nephrotic Syndrome

• NEJM: The Nephrotic Syndrome
• CJASN: Attending Rounds: An Older Patient with Nephrotic Syndrome
• NEJM: Glomerulonephritis Review

+ Critical Care Medicine

Full ATS reading list

Sepsis

• Early Goal Directed Therapy (EGDT) targeting on SVO2 >70, MAP >65, CVP 8-12, and UOP > 0.5mL/kg/hr reduces mortality in sepsis!
  • NEJM: EGDT Rivers Trial
• EGDT Does not reduce mortality... but perhaps early identification of sepsis with a focus on fluid resuscitation and antibiotics do.
  • NEJM: ARISE Trial
  • NEJM: Process Trial
  • NEJM: Promise Trial
• New Fancy Sepsis Guidelines
  • JAMA: 3rd International Consensus Definition of Sepsis
• Maybe we shouldn't keep changing the definition of Sepsis?
  • New Sepsis Criteria: A Change We Should Not Make

Fluid Management

• Conservative fluids in patient's with acute lung injury (ARDS) does not change mortality, but does decrease LoS in ICU and Vent time without increasing extra-pulmonary end-organ-damage
  • NEJM: FACTT Trial
• The use of colloids vs crystalloids in hypovolemia does not result in significant mortality difference at 28-days
  • NEJM: SAFE Trial

Steroids in Shock

• The majority of cortisol is protein bound and in the protein-depleted state of sepsis, measuring cortisol is clinically insignificant
  • NEJM: Cortisol in the ICU
• Hydrocortisone did not improve survival or reversal of shock in patients with septic shock, either overall or in patients who did not have a response to corticotropin, although hydrocortisone hastened reversal of shock in patients in whom shock was reversed.
  • NEJM: Steroids in Septic Shock Trial

Pressors

• Dopamine used to be first line in shock, now it is levophed (norepinephrine). This study showed no mortality difference between the two, but Dopamine had a significantly higher rate of cardiac complications
  • NEJM: Dopamine vs Levophed in Septic Shock
• MAPs of 65-70 have the same outcomes compared to MAPs of 80-85 in septic shock (this does not always hold true for all patients)
  • NEJM: High or Low MAP in Sepsis
• Can you put pressors in through a peripheral? Yes, it is safe although not ideal.
  • J. Hosp Med: Pressors through peripheral line can be safe

ARDS/Ventilation

• JAMA: Berlin ARDS
• Decreased delta of PIP/PEEP during ARDS ventilation is associated with improved survivorship.
  • NEJM: Driving Pressure in ARDS Ventilation
• Using 6ml/kg Vt in ARDS ventilation is associated with less Acute Lung Injury and Barotrauma, improving mortality.
  • NEJM: Low Tidal Volume in ARDS
• Ventilation Review
  • NEJM: NIPPV Overview

Hematology

• NEJM: Bleeding and Coagulopathies in Critical Care - 2014
• CHEST: Risk of Procedural Hemorrhage - 2016
• ACC: Management of Pulmonary Embolism - 2015

Right Heart Failure

• Crit Care: Management of Right Heart Failure - 2014

Sedation/Agitation

• AJHP: Pain Agitation and Delirium Guidelines
• Sedation and Delirium in ICU - NEJM 2014

Central Line

• NEJM: Intravascular Complications of Central Venous Catheterization by Insertion Site

GIB/Cirrhosis

• NEJM: Conservative vs Aggressive transfusion in GIB
• NEJM: TRICC Conservative Transfusion
• NEJM: TRISS Transfusion Trial
• NEJM: Lactulose +/- Rifaximin in Hepatic Encephalopathy

Toxicology

• CHEST: Adult Toxicology in Critical Care Part 1
• CHEST: Adult Toxicology in Critical Care Part 2
• CHEST: Adult Toxicology in Critical Care Part 3

Hypothermia

• NEJM: Hypothermia after arrest: 33 vs 36

+ Pulmonology

+ Science of Learning

• Academic Medicine: Six Strategies for Effective Learning
• Anesth Analog: The Cognitive Science of Learning - Concepts and Strategies for the Educator and Learner
• IMBES: Science Supports Education - The Behavioral Research Base for Psychology’s Top 20 Principles for Enhancing Teaching and Learning

+ Clinical Teaching

• Medical Teacher: Twelve Tips to Improve Medical Teaching Rounds
• Mayo Clinic Proceedings: Proposal for a Collaborative Approach to Clinical Teaching
• Medical Education: Applying the Science of Learning to Medical Education
• BMJ: ABC of Learning and Teaching Medicine - Applying Educational Theory in Practice
• ATS: Practical Strategies for Effective Lectures

+ Feedback

• Pediatrics: Going Beyond "Good Job" - How to Give Effective Feedback
• Guidelines - The Do's, Don'ts, and Don't Knows of Feedback for Medical Education